HSPMdb Accession NoHSPMDB002156
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameAV126
IUPAC Name4-[(propan-2-yloxy)carbonyl]phenyl 3-methanesulfonyl-4-methylbenzoate
SMILESCC(C)OC(=O)C1=CC=C(OC(=O)C2=CC=C(C)C(=C2)S(C)(=O)=O)C=C1
ClassNon beta lactone inhibitor
% Enzymatic Inhibition/Fold Change65% at 1 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002156

AV126

Physicochemical Properties