HSPMdb Accession NoHSPMDB002113
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameAV170
IUPAC Name4-acetylphenyl 3-(3,4,5-trimethoxyphenyl)propanoate
SMILESCOC1=CC(CCC(=O)OC2=CC=C(C=C2)C(C)=O)=CC(OC)=C1OC
ClassNon beta lactone inhibitor
% Enzymatic Inhibition/Fold Change25% at 1 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002113

AV170

Physicochemical Properties