HSPMdb Accession NoHSPMDB002104
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameAV168
IUPAC Name4-(1,3,4-oxadiazol-2-yl)phenyl 3-[methyl(3-sulfanylphenyl)sulfamoyl]benzoate
SMILESCN(C1=CC=CC(S)=C1)S(=O)(=O)C1=CC=CC(=C1)C(=O)OC1=CC=C(C=C1)C1=NN=CO1
ClassNon beta lactone inhibitor
% Enzymatic Inhibition/Fold Change30% at 10 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002104

AV168

Physicochemical Properties