HSPMdb Accession NoHSPMDB002091
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NamePalmostatin M
IUPAC Name(3S,4S)-3-decyl-4-[4-[3-(dimethylamino)propylsulfonyl]butyl]oxetan-2-one
SMILESCCCCCCCCCCC1C(OC1=O)CCCCS(=O)(=O)CCCN(C)C
ClassNon beta lactone inhibitor
IC50 (µM)21
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002091

Palmostatin M

Physicochemical Properties