HSPMdb Accession No | HSPMDB002081 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Antiproliferative activity |
Compound Name | DBeQ |
IUPAC Name | N2 , N4 -dibenzylquinazoline-2,4-diamine |
SMILES | C(Nc1nc(NCc2ccccc2)c3ccccc3n1)c4ccccc4 |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
GI50 (µM) | 6.6 |
Site of Interaction | Nucleotide binding domain |
Percentage Cell Growth Inhibition | 50% |
Cellular assay | Luminescence based viability assay |
Cellular Model | MRC-5 |