HSPMdb Accession NoHSPMDB002081
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activityAntiproliferative activity
Compound NameDBeQ
IUPAC NameN2 , N4 -dibenzylquinazoline-2,4-diamine
SMILESC(Nc1nc(NCc2ccccc2)c3ccccc3n1)c4ccccc4
ClassMaybridge, Hitfinder, and NIH molecular libraries
GI50 (µM)6.6
Site of InteractionNucleotide binding domain
Percentage Cell Growth Inhibition50%
Cellular assayLuminescence based viability assay
Cellular ModelMRC-5

Structure



HSPMDB002081

DBeQ

Physicochemical Properties