HSPMdb Accession No | HSPMDB002080 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Antiproliferative activity |
Compound Name | Mg132 |
IUPAC Name | benzyl N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate |
SMILES | CC(C)CC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1 |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
GI50 (µM) | 0.14 |
Site of Interaction | Nucleotide binding domain |
Percentage Cell Growth Inhibition | 50% |
Cellular assay | Luminescence based viability assay |
Cellular Model | RPMI8226 |