HSPMdb Accession NoHSPMDB002080
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activityAntiproliferative activity
Compound NameMg132
IUPAC Namebenzyl N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate
SMILESCC(C)CC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1
ClassMaybridge, Hitfinder, and NIH molecular libraries
GI50 (µM)0.14
Site of InteractionNucleotide binding domain
Percentage Cell Growth Inhibition50%
Cellular assayLuminescence based viability assay
Cellular ModelRPMI8226

Structure



HSPMDB002080

Mg132

Physicochemical Properties