HSPMdb Accession No | HSPMDB002076 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Substrate degradation activity |
Compound Name | KSC-16-5 |
IUPAC Name | 4-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]imino]cyclohexa-2,5-dien-1-one |
SMILES | C1=CC(=O)C=CC1=NC2=NC(=CS2)C3=CC=C(C=C3)Cl |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | 38 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | Reporter degradation assay (UbG76V-GFP) |
Cellular Model | HeLa |
Disease | Cancer |