HSPMdb Accession NoHSPMDB002076
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameKSC-16-5
IUPAC Name4-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]imino]cyclohexa-2,5-dien-1-one
SMILESC1=CC(=O)C=CC1=NC2=NC(=CS2)C3=CC=C(C=C3)Cl
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)38
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002076

KSC-16-5

Physicochemical Properties