HSPMdb Accession NoHSPMDB002075
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameMyriad 12/KSC-1-277
IUPAC Name4-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]amino]phenol
SMILESC1=CC(=CC=C1C2=CSC(=N2)NC3=CC=C(C=C3)O)Cl
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)16
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002075

Myriad 12/KSC-1-277

Physicochemical Properties