HSPMdb Accession NoHSPMDB002069
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameKSC-1-233/CID2044030
IUPAC NameN-(1-benzylpyrrolo[3,2-b]quinoxalin-2-yl)-4-chlorobenzenesulfonamide
SMILESC1=CC=C(C=C1)CN2C(=CC3=NC4=CC=CC=C4N=C32)NS(=O)(=O)C5=CC=C(C=C5)Cl
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)>30
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002069

KSC-1-233/CID2044030

Physicochemical Properties