HSPMdb Accession NoHSPMDB002067
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameKSC-1-205/CID5982653
IUPAC Name3-nitro-4-[(2E)-2-[(2,3,4-trihydroxyphenyl)methylidene]hydrazinyl]benzenesulfonamide
SMILESC1=CC(=C(C=C1S(=O)(=O)N)[N+](=O)[O-])NN=CC2=C(C(=C(C=C2)O)O)O
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)>30
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002067

KSC-1-205/CID5982653

Physicochemical Properties