HSPMdb Accession No | HSPMDB002063 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Substrate degradation activity |
Compound Name | CID2978460 |
IUPAC Name | 4-[[4-(2-fluorophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]sulfonylamino]benzoic acid |
SMILES | C1C=CC2C1C(NC3=C2C=C(C=C3)S(=O)(=O)NC4=CC=C(C=C4)C(=O)O)C5=CC=CC=C5F |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | >30 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | Reporter degradation assay (UbG76V-GFP) |
Cellular Model | HeLa |
Disease | Cancer |