HSPMdb Accession No | HSPMDB002061 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Substrate degradation activity |
Compound Name | CID1976446 |
IUPAC Name | (6E)-5-imino-6-[(4-oxochromen-3-yl)methylidene]-2-pyridin-4-yl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one |
SMILES | C1=CC=C2C(=C1)C(=O)C(=CO2)C=C3C(=N)N4C(=NC3=O)SC(=N4)C5=CC=NC=C5 |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | >30 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | Reporter degradation assay (UbG76V-GFP) |
Cellular Model | HeLa |
Disease | Cancer |