HSPMdb Accession NoHSPMDB002061
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameCID1976446
IUPAC Name(6E)-5-imino-6-[(4-oxochromen-3-yl)methylidene]-2-pyridin-4-yl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one
SMILESC1=CC=C2C(=C1)C(=O)C(=CO2)C=C3C(=N)N4C(=NC3=O)SC(=N4)C5=CC=NC=C5
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)>30
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002061

CID1976446

Physicochemical Properties