HSPMdb Accession NoHSPMDB002059
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameCID1625680
IUPAC Name4-[5-[(Z)-2-carboxy-2-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]ethenyl]furan-2-yl]-2-chlorobenzoic acid
SMILESCC1=NC(=NN1)SC(=CC2=CC=C(O2)C3=CC(=C(C=C3)C(=O)O)Cl)C(=O)O
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)>30
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002059

CID1625680

Physicochemical Properties