HSPMdb Accession NoHSPMDB002058
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameKSC-1-199/CID4072379
IUPAC NameN'-acridin-9-yl-2,4-dihydroxybenzohydrazide
SMILESC1=CC=C2C(=C1)C(=C3C=CC=CC3=N2)NNC(=O)C4=C(C=C(C=C4)O)O
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)68
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002058

KSC-1-199/CID4072379

Physicochemical Properties