HSPMdb Accession No | HSPMDB002057 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Substrate degradation activity |
Compound Name | KSC-1-209/CID2472581 |
IUPAC Name | [2-(1H-indol-3-yl)-2-oxoethyl] 5-nitrothiophene-2-carboxylate |
SMILES | C1=CC=C2C(=C1)C(=CN2)C(=O)COC(=O)C3=CC=C(S3)[N+](=O)[O-] |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | 66 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | Reporter degradation assay (UbG76V-GFP) |
Cellular Model | HeLa |
Disease | Cancer |