HSPMdb Accession NoHSPMDB002057
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameKSC-1-209/CID2472581
IUPAC Name[2-(1H-indol-3-yl)-2-oxoethyl] 5-nitrothiophene-2-carboxylate
SMILESC1=CC=C2C(=C1)C(=CN2)C(=O)COC(=O)C3=CC=C(S3)[N+](=O)[O-]
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)66
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002057

KSC-1-209/CID2472581

Physicochemical Properties