HSPMdb Accession NoHSPMDB002055
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameCID2175556
IUPAC Name4-[[4-(2,4-dihydroxyphenyl)-1,3-thiazol-2-yl]amino]benzenesulfonamide
SMILESC1=CC(=CC=C1NC2=NC(=CS2)C3=C(C=C(C=C3)O)O)S(=O)(=O)N
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)60
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002055

CID2175556

Physicochemical Properties