HSPMdb Accession NoHSPMDB002054
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameKSC-1-202/CID2810445
IUPAC Name2,6-dichloro-N-(2-hydroxy-1,3-dioxoinden-2-yl)benzamide
SMILESC1=CC=C2C(=C1)C(=O)C(C2=O)(NC(=O)C3=C(C=CC=C3Cl)Cl)O
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)42
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002054

KSC-1-202/CID2810445

Physicochemical Properties