HSPMdb Accession NoHSPMDB002053
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameKSC-1-1206/CID2384538
IUPAC Name2-(chloromethyl)-1H-pyrimido[1,2-a]benzimidazol-4-one
SMILESC1=CC=C2C(=C1)N=C3N2C(=O)C=C(N3)CCl
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)38
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002053

KSC-1-1206/CID2384538

Physicochemical Properties