HSPMdb Accession NoHSPMDB002051
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameCID16194309
IUPAC Name5-amino-6-[(Z)-(2-methylindol-3-ylidene)methyl]-3-(2-methylpropylsulfonyl)-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
SMILESCC1=NC2=CC=CC=C2C1=CC3=C(N4C(=NC3=O)SN=C4S(=O)(=O)CC(C)C)N
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)>30
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002051

CID16194309

Physicochemical Properties