HSPMdb Accession No | HSPMDB002051 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Substrate degradation activity |
Compound Name | CID16194309 |
IUPAC Name | 5-amino-6-[(Z)-(2-methylindol-3-ylidene)methyl]-3-(2-methylpropylsulfonyl)-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one |
SMILES | CC1=NC2=CC=CC=C2C1=CC3=C(N4C(=NC3=O)SN=C4S(=O)(=O)CC(C)C)N |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | >30 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | Reporter degradation assay (UbG76V-GFP) |
Cellular Model | HeLa |
Disease | Cancer |