HSPMdb Accession No | HSPMDB002046 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Substrate degradation activity |
Compound Name | SP01086 |
IUPAC Name | 3-(5-tert-butyl-2-methylfuran-3-yl)-4-methyl-5-(methylsulfanyl)-1H-pyrazole |
SMILES | CSC1=C(C)C(=NN1)C1=C(C)OC(=C1)C(C)(C)C |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | 23 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | Reporter degradation assay (UbG76V-GFP) |
Cellular Model | HeLa |
Disease | Cancer |