HSPMdb Accession NoHSPMDB002046
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameSP01086
IUPAC Name3-(5-tert-butyl-2-methylfuran-3-yl)-4-methyl-5-(methylsulfanyl)-1H-pyrazole
SMILESCSC1=C(C)C(=NN1)C1=C(C)OC(=C1)C(C)(C)C
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)23
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002046

SP01086

Physicochemical Properties