HSPMdb Accession NoHSPMDB002045
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameCD02660
IUPAC Nameethyl 3-[(E)-[(3,5-dichloro-2-hydroxyphenyl)methylidene]amino]-4-oxo-3,4-dihydroquinazoline-2-carboxylate
SMILESCCOC(=O)C1=NC2=C(C=CC=C2)C(=O)N1\N=C\C1=C(O)C(Cl)=CC(Cl)=C1
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)23
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002045

CD02660

Physicochemical Properties