HSPMdb Accession No | HSPMDB002045 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Substrate degradation activity |
Compound Name | CD02660 |
IUPAC Name | ethyl 3-[(E)-[(3,5-dichloro-2-hydroxyphenyl)methylidene]amino]-4-oxo-3,4-dihydroquinazoline-2-carboxylate |
SMILES | CCOC(=O)C1=NC2=C(C=CC=C2)C(=O)N1\N=C\C1=C(O)C(Cl)=CC(Cl)=C1 |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | 23 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | Reporter degradation assay (UbG76V-GFP) |
Cellular Model | HeLa |
Disease | Cancer |