HSPMdb Accession No | HSPMDB002041 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Substrate degradation activity |
Compound Name | HTS01888 |
IUPAC Name | N-[4-(3-Chloro-4-methylphenyl)-5-methyl-1,3-thiazol-2-yl]-2,1,3-benzoxadiazole-4-sulfonamide |
SMILES | Cc1ccc(cc1Cl)c2nc(NS(=O)(=O)c3cccc4nonc34)sc2C |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | 19 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | Reporter degradation assay (UbG76V-GFP) |
Cellular Model | HeLa |
Disease | Cancer |