HSPMdb Accession NoHSPMDB002040
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameSPB01017
IUPAC Name[1-(1,3-dithiolan-2-yl)naphthalen-2-yl] thiophene-2-carboxylate
SMILESC1CSC(S1)C2=C(C=CC3=CC=CC=C32)OC(=O)C4=CC=CS4
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)19
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002040

SPB01017

Physicochemical Properties