HSPMdb Accession NoHSPMDB002039
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameCID6524677
IUPAC Name(4Z)-4-[[2-(7-chloroquinolin-4-yl)hydrazinyl]methylidene]-2-hydroxycyclohexa-2,5-dien-1-one
SMILESC1=CC2=C(C=CN=C2C=C1Cl)NNC=C3C=CC(=O)C(=C3)O
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)15
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002039

CID6524677

Physicochemical Properties