HSPMdb Accession No | HSPMDB002038 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Substrate degradation activity |
Compound Name | KSC-1-128/CID987585 |
IUPAC Name | N-(1-benzyl-3-cyanopyrrolo[3,2-b]quinoxalin-2-yl)-2-chlorobenzamide |
SMILES | C1=CC=C(C=C1)CN2C(=C(C3=NC4=CC=CC=C4N=C32)C#N)NC(=O)C5=CC=CC=C5Cl |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | 17 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | Reporter degradation assay (UbG76V-GFP) |
Cellular Model | HeLa |
Disease | Cancer |