HSPMdb Accession NoHSPMDB002037
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameKSC-1-131/CID2867539/CID/9567210
IUPAC Name3-[(2E)-2-[(4-methoxyphenyl)methylidene]hydrazinyl]-6-phenyl-4H-1,2,4-triazin-5-one
SMILESCOC1=CC=C(C=C1)C=NNC2=NN=C(C(=O)N2)C3=CC=CC=C3
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)16
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002037

KSC-1-131/CID2867539/CID/9567210

Physicochemical Properties