HSPMdb Accession No | HSPMDB002037 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Substrate degradation activity |
Compound Name | KSC-1-131/CID2867539/CID/9567210 |
IUPAC Name | 3-[(2E)-2-[(4-methoxyphenyl)methylidene]hydrazinyl]-6-phenyl-4H-1,2,4-triazin-5-one |
SMILES | COC1=CC=C(C=C1)C=NNC2=NN=C(C(=O)N2)C3=CC=CC=C3 |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | 16 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | Reporter degradation assay (UbG76V-GFP) |
Cellular Model | HeLa |
Disease | Cancer |