HSPMdb Accession NoHSPMDB002036
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameCID5413643
IUPAC Name2-[4-methyl-6-(phenylamino)pyrimidin-2-yl]phenol
SMILESCC1=CC(NC2=CC=CC=C2)=NC(=N1)C1=C(O)C=CC=C1
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)16
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002036

CID5413643

Physicochemical Properties