HSPMdb Accession No | HSPMDB002034 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Substrate degradation activity |
Compound Name | KSC-1-130/CID9586497 |
IUPAC Name | 2-[(E)-[4-[(2,4-dichlorophenyl)methoxy]phenyl]methylideneamino]guanidine |
SMILES | C1=CC(=CC=C1C=NN=C(N)N)OCC2=C(C=C(C=C2)Cl)Cl |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | 11 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | Reporter degradation assay (UbG76V-GFP) |
Cellular Model | HeLa |
Disease | Cancer |