HSPMdb Accession NoHSPMDB002034
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameKSC-1-130/CID9586497
IUPAC Name2-[(E)-[4-[(2,4-dichlorophenyl)methoxy]phenyl]methylideneamino]guanidine
SMILESC1=CC(=CC=C1C=NN=C(N)N)OCC2=C(C=C(C=C2)Cl)Cl
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)11
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002034

KSC-1-130/CID9586497

Physicochemical Properties