HSPMdb Accession No | HSPMDB002032 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Substrate degradation activity |
Compound Name | CID1109468 |
IUPAC Name | 5-amino-4-cyano-N-[(2-methoxynaphthalen-1-yl)methylideneamino]-3-methylthiophene-2-carboxamide |
SMILES | CC1=C(SC(=C1C#N)N)C(=O)NN=CC2=C(C=CC3=CC=CC=C32)OC |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | 10 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | Reporter degradation assay (UbG76V-GFP) |
Cellular Model | HeLa |
Disease | Cancer |