| HSPMdb Accession No | HSPMDB002031 |
| PMID | 21383145 |
| Target | Hsp100 |
| HSP Name | p97 |
| Organism | Human |
| Localization | Cytosol |
| Cellular activity | Substrate degradation activity |
| Compound Name | SEW05182 |
| IUPAC Name | 5-({5-[2-chloro-5-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione |
| SMILES | CC1(C)OC(=O)C(=CC2=CC=C(O2)C2=C(Cl)C=CC(=C2)C(F)(F)F)C(=O)O1 |
| Class | Maybridge, Hitfinder, and NIH molecular libraries |
| IC50 (µM) | 7.5 |
| Site of Interaction | Nucleotide binding domain |
| Cellular assay | Reporter degradation assay (UbG76V-GFP) |
| Cellular Model | HeLa |
| Disease | Cancer |
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