HSPMdb Accession No | HSPMDB002030 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Substrate degradation activity |
Compound Name | JFD00597 |
IUPAC Name | 3-(1,3-benzoxazol-2-ylthio)-5,5-dimethylcyclohex-2-en-1-one |
SMILES | O1C(=NC2=C1C=CC=C2)SC2=CC(CC(C2)(C)C)=O |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | 6.6 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | Reporter degradation assay (UbG76V-GFP) |
Cellular Model | HeLa |
Disease | Cancer |