HSPMdb Accession NoHSPMDB002030
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameJFD00597
IUPAC Name3-(1,3-benzoxazol-2-ylthio)-5,5-dimethylcyclohex-2-en-1-one
SMILESO1C(=NC2=C1C=CC=C2)SC2=CC(CC(C2)(C)C)=O
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)6.6
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002030

JFD00597

Physicochemical Properties