HSPMdb Accession No | HSPMDB002027 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Substrate degradation activity |
Compound Name | JFD02342 |
IUPAC Name | 1-(4-Methylphenyl)-3-phenyl-2-propyn-1-one |
SMILES | CC1=CC=C(C=C1)C(=O)C#CC2=CC=CC=C2 |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | 3.4 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | Reporter degradation assay (UbG76V-GFP) |
Cellular Model | HeLa |
Disease | Cancer |