HSPMdb Accession NoHSPMDB002026
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameKSC-1-127/CID6763
IUPAC Namephenanthrene-9,10-dione
SMILESC1=CC=C2C(=C1)C3=CC=CC=C3C(=O)C2=O
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)1.3
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002026

KSC-1-127/CID6763

Physicochemical Properties