HSPMdb Accession NoHSPMDB002025
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameJFD03665
IUPAC Name(10E)-10-(hydroxymethylidene)-9,10-dihydrophenanthren-9-one
SMILESO\C=C1\C(=O)C2=C(C=CC=C2)C2=C1C=CC=C2
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)1.1
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002025

JFD03665

Physicochemical Properties