HSPMdb Accession NoHSPMDB002024
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameKSC-1-150/CID886813
IUPAC NameN-benzyl-2-(2-fluorophenyl)quinazolin-4-amine
SMILESFc1ccccc1c2nc(NCc3ccccc3)c4ccccc4n2
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)9
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002024

KSC-1-150/CID886813

Physicochemical Properties