HSPMdb Accession NoHSPMDB002023
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Cellular activitySubstrate degradation activity
Compound NameCID16472035/CID676352
IUPAC Name2-N,4-N-dibenzylquinazoline-2,4-diamine;hydrochloride
SMILESC1=CC=C(C=C1)CNC2=NC(=NC3=CC=CC=C32)NCC4=CC=CC=C4.Cl
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)2.6
Site of InteractionNucleotide binding domain
Cellular assayReporter degradation assay (UbG76V-GFP)
Cellular ModelHeLa
DiseaseCancer

Structure



HSPMDB002023

CID16472035/CID676352

Physicochemical Properties