HSPMdb Accession No | HSPMDB002023 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Cellular activity | Substrate degradation activity |
Compound Name | CID16472035/CID676352 |
IUPAC Name | 2-N,4-N-dibenzylquinazoline-2,4-diamine;hydrochloride |
SMILES | C1=CC=C(C=C1)CNC2=NC(=NC3=CC=CC=C32)NCC4=CC=CC=C4.Cl |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | 2.6 |
Site of Interaction | Nucleotide binding domain |
Cellular assay | Reporter degradation assay (UbG76V-GFP) |
Cellular Model | HeLa |
Disease | Cancer |