HSPMdb Accession No | HSPMDB002012 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | KSC-1-133/CID5559718 |
IUPAC Name | (Z)-2-(1,3-benzothiazol-2-yl)-3-hydroxy-4-(4-methylphenyl)sulfanylbut-2-enenitrile |
SMILES | CC1=CC=C(C=C1)SCC(=C(C#N)C2=NC3=CC=CC=C3S2)O |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | 8.8 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | ATPase assay |