HSPMdb Accession NoHSPMDB001987
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity
Compound NameHTS01888
IUPAC NameN-[4-(3-Chloro-4-methylphenyl)-5-methyl-1,3-thiazol-2-yl]-2,1,3-benzoxadiazole-4-sulfonamide
SMILESCc1ccc(cc1Cl)c2nc(NS(=O)(=O)c3cccc4nonc34)sc2C
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)19
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB001987

HTS01888

Physicochemical Properties