HSPMdb Accession No | HSPMDB001981 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | KSC-1-204/CID3500086 |
IUPAC Name | 2-(5-chloro-1-ethyl-3-nitro-6-oxopyridazin-4-yl)-2-[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]acetonitrile |
SMILES | CCN1C(=O)C(=C(C(=N1)[N+](=O)[O-])C(C#N)C2=NC3=C(S2)C=CC(=C3)C(F)(F)F)Cl |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | 14 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | ATPase assay |