HSPMdb Accession No | HSPMDB001977 |
PMID | 21383145 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Human |
Localization | Cytosol |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | SEW05182 |
IUPAC Name | 5-({5-[2-chloro-5-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione |
SMILES | CC1(C)OC(=O)C(=CC2=CC=C(O2)C2=C(Cl)C=CC(=C2)C(F)(F)F)C(=O)O1 |
Class | Maybridge, Hitfinder, and NIH molecular libraries |
IC50 (µM) | 13 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | ATPase assay |