HSPMdb Accession NoHSPMDB001977
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity
Compound NameSEW05182
IUPAC Name5-({5-[2-chloro-5-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione
SMILESCC1(C)OC(=O)C(=CC2=CC=C(O2)C2=C(Cl)C=CC(=C2)C(F)(F)F)C(=O)O1
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)13
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB001977

SEW05182

Physicochemical Properties