HSPMdb Accession NoHSPMDB001962
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity
Compound NameKSC-1-133/CID5559718
IUPAC Name(Z)-2-(1,3-benzothiazol-2-yl)-3-hydroxy-4-(4-methylphenyl)sulfanylbut-2-enenitrile
SMILESCC1=CC=C(C=C1)SCC(=C(C#N)C2=NC3=CC=CC=C3S2)O
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)50
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB001962

KSC-1-133/CID5559718

Physicochemical Properties