HSPMdb Accession NoHSPMDB001947
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity
Compound NameCID16194309
IUPAC Name5-amino-6-[(Z)-(2-methylindol-3-ylidene)methyl]-3-(2-methylpropylsulfonyl)-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
SMILESCC1=NC2=CC=CC=C2C1=CC3=C(N4C(=NC3=O)SN=C4S(=O)(=O)CC(C)C)N
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)12
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB001947

CID16194309

Physicochemical Properties