HSPMdb Accession NoHSPMDB001931
PMID21383145
TargetHsp100
HSP Namep97
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity
Compound NameKSC-1-204/CID3500086
IUPAC Name2-(5-chloro-1-ethyl-3-nitro-6-oxopyridazin-4-yl)-2-[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]acetonitrile
SMILESCCN1C(=O)C(=C(C(=N1)[N+](=O)[O-])C(C#N)C2=NC3=C(S2)C=CC(=C3)C(F)(F)F)Cl
ClassMaybridge, Hitfinder, and NIH molecular libraries
IC50 (µM)52
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB001931

KSC-1-204/CID3500086

Physicochemical Properties