HSPMdb Accession NoHSPMDB001914
PMID30571121
TargetHsp100
OrganismBacteria
Cellular activityAntibacterial activity
Compound Name107
IUPAC NameB e n z y l ( ( 3 - C y a n o - 4 - ( p i p e r a z i n - 1 - y l ) p h e n y l ) -(diphenoxyphosphoryl)methyl)carbamate 2,2,2-trifluoroacetate
SMILESO=C(OCC1=CC=CC=C1)NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)C4=CC=C(N5CCNCC5)C=C4.O=C(O)C(F)(F)F
ClassSerine protease inhibitor library
Percentage Cell Growth Inhibition69.90%
Cellular assayBacterial growth inhibition assay (OD based)
Cellular ModelE. coli tolC deleted (JW5503)
DiseaseBacterial infection

Structure



HSPMDB001914

107

Physicochemical Properties