HSPMdb Accession No | HSPMDB001914 |
PMID | 30571121 |
Target | Hsp100 |
Organism | Bacteria |
Cellular activity | Antibacterial activity |
Compound Name | 107 |
IUPAC Name | B e n z y l ( ( 3 - C y a n o - 4 - ( p i p e r a z i n - 1 - y l ) p h e n y l ) -(diphenoxyphosphoryl)methyl)carbamate 2,2,2-trifluoroacetate |
SMILES | O=C(OCC1=CC=CC=C1)NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)C4=CC=C(N5CCNCC5)C=C4.O=C(O)C(F)(F)F |
Class | Serine protease inhibitor library |
Percentage Cell Growth Inhibition | 69.90% |
Cellular assay | Bacterial growth inhibition assay (OD based) |
Cellular Model | E. coli tolC deleted (JW5503) |
Disease | Bacterial infection |