HSPMdb Accession NoHSPMDB001910
PMID30571121
TargetHsp100
OrganismHuman
Cellular activityAntiproliferative activity
Compound Name107
IUPAC NameB e n z y l ( ( 3 - C y a n o - 4 - ( p i p e r a z i n - 1 - y l ) p h e n y l ) -(diphenoxyphosphoryl)methyl)carbamate 2,2,2-trifluoroacetate
SMILESO=C(OCC1=CC=CC=C1)NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)C4=CC=C(N5CCNCC5)C=C4.O=C(O)C(F)(F)F
ClassSerine protease inhibitor library
EC50 (µM)0.4
Cellular assayLuminescence based viability assay
Cellular ModelA549
DiseaseCancer

Structure



HSPMDB001910

107

Physicochemical Properties