HSPMdb Accession NoHSPMDB001899
PMID30571121
TargetHsp100
OrganismHuman
Cellular activityAntiproliferative activity
Compound Name53
IUPAC NameDiphenyl (2-(4-Guanidinophenyl)-1-((S)-2-((S)-3-hydroxy-2-(thiophene-2-carboxamido)propanamido)propanamido)ethyl)-phosphonate
SMILESC[C@H](NC([C@@H](NC(C1=CC=CS1)=O)CO)=O)C(NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)CC4=CC=C(NC(N)=N)C=C4)=O
ClassSerine protease inhibitor library
EC50 (µM)100
Cellular assayLuminescence based viability assay
Cellular ModelA549
DiseaseCancer

Structure



HSPMDB001899

53

Physicochemical Properties