HSPMdb Accession NoHSPMDB001868
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name147
IUPAC NameMethyl ((Bis(4-acetamidophenoxy)phosphoryl)(3-carbamimidoylphenyl)methyl)carbamate
SMILESO=C(OC(P(OC1=CC=C(NC(C)=O)C=C1)(OC2=CC=C(NC(C)=O)C=C2)=O)C3=CC=CC(C(N)=N)=C3)NC
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change12% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001868

147

Physicochemical Properties