HSPMdb Accession NoHSPMDB001867
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name146
IUPAC NameBenzyl ( ( B is(4-acetamidophenoxy)phosphoryl)( 3-carbamimidoylphenyl)methyl)carbamate
SMILESO=C(OC(P(OC1=CC=C(NC(C)=O)C=C1)(OC2=CC=C(NC(C)=O)C=C2)=O)C3=CC=CC(C(N)=N)=C3)NCC4=CC=CC=C4
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change29% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001867

146

Physicochemical Properties