HSPMdb Accession No | HSPMDB001867 |
PMID | 30571121 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 146 |
IUPAC Name | Benzyl ( ( B is(4-acetamidophenoxy)phosphoryl)( 3-carbamimidoylphenyl)methyl)carbamate |
SMILES | O=C(OC(P(OC1=CC=C(NC(C)=O)C=C1)(OC2=CC=C(NC(C)=O)C=C2)=O)C3=CC=CC(C(N)=N)=C3)NCC4=CC=CC=C4 |
Class | Serine protease inhibitor library |
% Enzymatic Inhibition/Fold Change | 29% at 200 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |