HSPMdb Accession No | HSPMDB001863 |
PMID | 30571121 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 136 |
IUPAC Name | Benzo[d][1,3]dioxol-5-ylmethyl ((3-Aminophenyl)-(diphenoxyphosphoryl)methyl)carbamate |
SMILES | O=C(OCC1=CC=C(OCO2)C2=C1)NC(C3=CC=CC(N)=C3)P(OC4=CC=CC=C4)(OC5=CC=CC=C5)=O |
Class | Serine protease inhibitor library |
% Enzymatic Inhibition/Fold Change | 20% at 200 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |