HSPMdb Accession No | HSPMDB001861 |
PMID | 30571121 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 130 |
IUPAC Name | Methyl (1-(Bis(4-acetamidophenoxy)phosphoryl)-2-(4-(trifluoromethyl)phenyl)ethyl)carbamate |
SMILES | O=C(OC)NC(P(OC1=CC=C(NC(C)=O)C=C1)(OC2=CC=C(NC(C)=O)C=C2)=O)CC3=CC=C(C(F)(F)F)C=C3 |
Class | Serine protease inhibitor library |
% Enzymatic Inhibition/Fold Change | 20% at 200 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |